Because ATL contains guanidine hydrochloride, it inactivates nucleases and denatures proteins, making it ideal for obtaining high-molecular-weight genomic DNA from archived or fresh tissues.
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QIAGEN ATL Buffer (Animal Tissue Lysis Buffer) is a specialized enzymatic lysis solution designed for the pretreatment of tough biological samples prior to DNA purification. It is a key component of QIAGEN’s DNeasy® and QIAamp® DNA kits. Because ATL contains guanidine hydrochloride